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Functional heterogeneity of the four voltage sensors of a human L-type calcium channel

Excitation-evoked Ca(2+) influx is the fastest and most ubiquitous chemical trigger for cellular processes, including neurotransmitter release, muscle contraction, and gene expression. The voltage dependence and timing of Ca(2+) entry are thought to be functions of voltage-gated calcium (Ca(V)) chan...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Pantazis, Antonios, Savalli, Nicoletta, Sigg, Daniel, Neely, Alan, Olcese, Riccardo
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280600/
https://ncbi.nlm.nih.gov/pubmed/25489110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411127112
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