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The RCK2 domain of the human BK(Ca) channel is a calcium sensor

Large conductance voltage and Ca(2+)-dependent K(+) channels (BK(Ca)) are activated by both membrane depolarization and intracellular Ca(2+). Recent studies on bacterial channels have proposed that a Ca(2+)-induced conformational change within specialized regulators of K(+) conductance (RCK) domains...

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Autors principals: Yusifov, Taleh, Savalli, Nicoletta, Gandhi, Chris S., Ottolia, Michela, Olcese, Riccardo
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224220/
https://ncbi.nlm.nih.gov/pubmed/18162557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705261105
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