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Hypermutation in human cancer genomes: footprints and mechanisms
A role for somatic mutations in carcinogenesis is well accepted, but the degree to which mutation rates influence cancer initiation and development is under continuous debate. Recently accumulated genomic data has revealed that thousands of tumour samples are riddled by hypermutation, broadening sup...
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| Veröffentlicht in: | Nat Rev Cancer |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4280484/ https://ncbi.nlm.nih.gov/pubmed/25568919 |
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