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Mechanisms of TNFα antagonist-induced lupus in a murine model
OBJECTIVE: TNFα antagonists are effective for treating rheumatoid arthritis and other inflammatory diseases, but their use can be complicated by lupus-like phenomena. We investigated the role of TNFα in murine lupus. METHODS: TLR7 ligand-driven lupus was induced in B6 and B6-TNFα(−/−) mice using pri...
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| Publié dans: | Arthritis Rheumatol |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4280290/ https://ncbi.nlm.nih.gov/pubmed/25252121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38882 |
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