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Tumor necrosis factor-α inhibition attenuates middle cerebral artery remodeling but increases cerebral ischemic damage in hypertensive rats

Hypertension causes vascular inflammation evidenced by an increase in perivascular macrophages and proinflammatory cytokines in the arterial wall. Perivascular macrophage depletion reduced tumor necrosis factor (TNF)-α expression in cerebral arteries of hypertensive rats and attenuated inward remode...

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Bibliografske podrobnosti
izdano v:Am J Physiol Heart Circ Physiol
Main Authors: Pires, Paulo W., Girgla, Saavia S., Moreno, Guillermo, McClain, Jonathon L., Dorrance, Anne M.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280151/
https://ncbi.nlm.nih.gov/pubmed/25015967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00018.2014
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