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On the Modularity of the Intrinsic Flexibility of the µ Opioid Receptor: A Computational Study
The µ opioid receptor (µOR), the principal target to control pain, belongs to the G protein-coupled receptors (GPCRs) family, one of the most highlighted protein families due to their importance as therapeutic targets. The conformational flexibility of GPCRs is one of their essential characteristics...
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| Udgivet i: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4280117/ https://ncbi.nlm.nih.gov/pubmed/25549261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115856 |
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