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On the Modularity of the Intrinsic Flexibility of the µ Opioid Receptor: A Computational Study

The µ opioid receptor (µOR), the principal target to control pain, belongs to the G protein-coupled receptors (GPCRs) family, one of the most highlighted protein families due to their importance as therapeutic targets. The conformational flexibility of GPCRs is one of their essential characteristics...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Fossépré, Mathieu, Leherte, Laurence, Laaksonen, Aatto, Vercauteren, Daniel P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280117/
https://ncbi.nlm.nih.gov/pubmed/25549261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115856
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