Robust dose-response curve estimation applied to high content screening data analysis

BACKGROUND AND METHOD: Successfully automated sigmoidal curve fitting is highly challenging when applied to large data sets. In this paper, we describe a robust algorithm for fitting sigmoid dose-response curves by estimating four parameters (floor, window, shift, and slope), together with the detec...

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Vydáno v:Source Code Biol Med
Hlavní autoři: Nguyen, Thuy Tuong, Song, Kyungmin, Tsoy, Yury, Kim, Jin Yeop, Kwon, Yong-Jun, Kang, Myungjoo, Edberg Hansen, Michael Adsetts
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279979/
https://ncbi.nlm.nih.gov/pubmed/25614758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13029-014-0027-x
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