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Transcriptome profiling and pathway analysis of genes expressed differentially in participants with or without a positive response to topiramate treatment for methamphetamine addiction

BACKGROUND: Developing efficacious medications to treat methamphetamine dependence is a global challenge in public health. Topiramate (TPM) is undergoing evaluation for this indication. The molecular mechanisms underlying its effects are largely unknown. Examining the effects of TPM on genome-wide g...

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Veröffentlicht in:BMC Med Genomics
Hauptverfasser: Li, Ming D, Wang, Ju, Niu, Tianhua, Ma, Jennie Z, Seneviratne, Chamindi, Ait-Daoud, Nassima, Saadvandi, Jim, Morris, Rana, Weiss, David, Campbell, Jan, Haning, William, Mawhinney, David J, Weis, Denis, McCann, Michael, Stock, Christopher, Kahn, Roberta, Iturriaga, Erin, Yu, Elmer, Elkashef, Ahmed, Johnson, Bankole A
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279796/
https://ncbi.nlm.nih.gov/pubmed/25495887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-014-0065-x
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