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Susceptibility locus in neurokinin-1 receptor gene associated with alcohol dependence
Substance P (SP), a neurotransmitter in stress pathways, exerts its effects mainly through the neurokinin-1 receptor (NK1R). Genetic and pharmacologic studies show that binding of ligands to NK1R decreases anxiety-related behaviors and therefore self-administration of alcohol in mice and craving for...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2743763/ https://ncbi.nlm.nih.gov/pubmed/19553914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2009.65 |
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