Susceptibility locus in neurokinin-1 receptor gene associated with alcohol dependence

Substance P (SP), a neurotransmitter in stress pathways, exerts its effects mainly through the neurokinin-1 receptor (NK1R). Genetic and pharmacologic studies show that binding of ligands to NK1R decreases anxiety-related behaviors and therefore self-administration of alcohol in mice and craving for...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Seneviratne, Chamindi, Ait-Daoud, Nassima, Ma, Jennie Z., Chen, Guobo, Johnson, Bankole A., Li, Ming D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743763/
https://ncbi.nlm.nih.gov/pubmed/19553914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2009.65
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg