A 90-day study of sub-chronic oral toxicity of 20 nm positively charged zinc oxide nanoparticles in Sprague Dawley rats

PURPOSE: The study reported here was conducted to determine the systemic oral toxicity and to find the no-observed-adverse-effect level of 20 nm positively charged zinc oxide (ZnO(SM20(+))) nanoparticles in Sprague Dawley rats for 90 days. METHODS: For the 90-day toxicity study, the high dose was se...

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Bibliographic Details
Published in:Int J Nanomedicine
Main Authors: Park, Hark-Soo, Kim, Seon-Ju, Lee, Taek-Jin, Kim, Geon-Yong, Meang, EunHo, Hong, Jeong-Sup, Kim, Su-Hyon, Koh, Sang-Bum, Hong, Seung-Guk, Sun, Yle-Shik, Kang, Jin Seok, Kim, Yu-Ri, Kim, Meyoung-Kon, Jeong, Jayoung, Lee, Jong-Kwon, Son, Woo-Chan, Park, Jae-Hak
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2014
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279754/
https://ncbi.nlm.nih.gov/pubmed/25565829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S57927
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