Paradoxical role of CBX8 in proliferation and metastasis of colorectal cancer

The effect of polycomb chromobox (Cbx) proteins in cancer is context-dependent. The Chromobox homolog 8 (CBX8) was originally characterized as a transcriptional repressor, which inhibits cell proliferation in Ink4a-Arf-dependent and -independent manner. However, the role of CBX8 in colorectal cancer...

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Pubblicato in:Oncotarget
Autori principali: Tang, Jianjun, Wang, Gang, Zhang, Meifang, Li, Feng-yan, Sang, Yi, Wang, Boqing, Hu, Kaishun, Wu, Yuanzhong, Luo, Rongzhen, Liao, Dan, Cao, Jingying, Wang, Xin, Wang, Li, Zhang, Ruhua, Zhang, Xiaoshi, Deng, Wu-Guo, Xie, Dan, Xu, Rui-hua, Kang, Tiebang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2014
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279409/
https://ncbi.nlm.nih.gov/pubmed/25360999
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