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Linifanib Versus Sorafenib in Patients With Advanced Hepatocellular Carcinoma: Results of a Randomized Phase III Trial

PURPOSE: This open-label phase III trial evaluated efficacy and tolerability of linifanib versus sorafenib in patients with advanced hepatocellular carcinoma (HCC) without prior systemic therapy. PATIENTS AND METHODS: Patients were randomly assigned in a 1:1 ratio to linifanib 17.5 mg once daily or...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Cainap, Calin, Qin, Shukui, Huang, Wen-Tsung, Chung, Ik Joo, Pan, Hongming, Cheng, Ying, Kudo, Masatoshi, Kang, Yoon-Koo, Chen, Pei-Jer, Toh, Han-Chong, Gorbunova, Vera, Eskens, Ferry A.L.M., Qian, Jiang, McKee, Mark D., Ricker, Justin L., Carlson, Dawn M., El-Nowiem, Saied
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279237/
https://ncbi.nlm.nih.gov/pubmed/25488963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2013.54.3298
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