Minimizing the Non-specific Binding of Nanoparticles to the Brain Enables Active Targeting of Fn14-positive Glioblastoma Cells

A major limitation in the treatment of glioblastoma (GBM), the most common and deadly primary brain cancer, is delivery of therapeutics to invading tumor cells outside of the area that is safe for surgical removal. A promising way to target invading GBM cells is via drug-loaded nanoparticles that bi...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Schneider, Craig S., Perez, Jimena G., Cheng, Emily, Zhang, Clark, Mastorakos, Panagiotis, Hanes, Justin, Winkles, Jeffrey A., Woodworth, Graeme F., Kim, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279109/
https://ncbi.nlm.nih.gov/pubmed/25542792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.11.054
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