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Biology of IL-27 and its Role in the Host Immunity against Mycobacterium Tuberculosis
IL-27, a heterodimeric cytokine of IL-12 family, regulates both innate and adaptive immunity largely via Jak-Stat signaling. IL-27 can induce IFN-γ and inflammatory mediators from T lymphocytes and innate immune cells. IL-27 has unique anti-inflammatory properties via both Tr1 cells dependent and in...
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| Udgivet i: | Int J Biol Sci |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Ivyspring International Publisher
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4279092/ https://ncbi.nlm.nih.gov/pubmed/25561899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.10464 |
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