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Quantitative Structure-Pharmacokinetic Relationships for the Prediction of Renal Clearance in Humans
Renal clearance (CL(R)), a major route of elimination for many drugs and drug metabolites, represents the net result of glomerular filtration, active secretion and reabsorption, and passive reabsorption. The aim of this study was to develop quantitative structure-pharmacokinetic relationships (QSPKR...
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| Publicado no: | Drug Metab Dispos |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4279087/ https://ncbi.nlm.nih.gov/pubmed/25352657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.114.059857 |
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