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Inhibition of Human Aldehyde Oxidase Activity by Diet-Derived Constituents: Structural Influence, Enzyme-Ligand Interactions, and Clinical Relevance

The mechanistic understanding of interactions between diet-derived substances and conventional medications in humans is nascent. Most investigations have examined cytochrome P450–mediated interactions. Interactions mediated by other phase I enzymes are understudied. Aldehyde oxidase (AO) is a phase...

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Vydáno v:Drug Metab Dispos
Hlavní autoři: Barr, John T., Jones, Jeffrey P., Oberlies, Nicholas H., Paine, Mary F.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279085/
https://ncbi.nlm.nih.gov/pubmed/25326286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.114.061192
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