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ERCC1 Induction after Oxaliplatin Exposure May Depend on KRAS Mutational Status in Colorectal Cancer Cell Line: In Vitro Veritas

Introduction: Oxaliplatin (Oxa) is widely used in metastatic colorectal cancer (mCRC), but currently there are not valid predictors of response to this drug. In the control arms both of OPUS and PRIME studies Oxa seems more active in patients with mCRC with mutated (mt) KRAS than in those with wild...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cancer
Hauptverfasser: Orlandi, A., Di Salvatore, M., Bagalà, C., Basso, M., Strippoli, A., Plastino, F., Calegari, M.A., Cassano, A., Astone, A., Barone, C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278917/
https://ncbi.nlm.nih.gov/pubmed/25553091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.10478
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