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The Vitamin D Receptor Inhibits the Respiratory Chain, Contributing to the Metabolic Switch that Is Essential for Cancer Cell Proliferation

We recently described the mitochondrial localization and import of the vitamin D receptor (VDR) in actively proliferating HaCaT cells for the first time, but its role in the organelle remains unknown. Many metabolic intermediates that support cell growth are provided by the mitochondria; consequentl...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Consiglio, Marco, Destefanis, Michele, Morena, Deborah, Foglizzo, Valentina, Forneris, Mattia, Pescarmona, Gianpiero, Silvagno, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278832/
https://ncbi.nlm.nih.gov/pubmed/25546457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115816
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