Epim(−/−) mice are partially protected from acute colitis via decreased IL-6 signaling

Epimorphin (Epim), a member of the syntaxin family of membrane bound, intracellular vesicle docking proteins, is expressed in intestinal myofibroblasts and macrophages. We have previously demonstrated that Epim(−/−) mice are partially protected from dextran sodium sulfate (DSS)-induced colitis. Whil...

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Bibliographic Details
Published in:Transl Res
Main Authors: Shaker, Anisa, Gargus, Matthew, Fink, Julie, Binkley, Jana, Darwech, Isra, Swietlicki, Elzbieta, Levin, Marc S., Rubin, Deborah C.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278761/
https://ncbi.nlm.nih.gov/pubmed/24731292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2014.03.007
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