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Postsynaptic density protein 95-regulated NR2B tyrosine phosphorylation and interactions of Fyn with NR2B in levodopa-induced dyskinesia rat models

CONTEXT: Abnormality in interactions between N-methyl-d-aspartate (NMDA) receptor and its signaling molecules occurs in the lesioned striatum in Parkinson’s disease (PD) and levodopa-induced dyskinesia (LID). It was reported that Fyn-mediated NR2B tyrosine phosphorylation, can enhance NMDA receptor...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Ba, Maowen, Kong, Min, Ma, Guozhao
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278739/
https://ncbi.nlm.nih.gov/pubmed/25565773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S75495
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