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Forkhead Box Protein O3 Transcription Factor Negatively Regulates Autophagy in Human Cancer Cells by Inhibiting Forkhead Box Protein O1 Expression and Cytosolic Accumulation

FoxO proteins are important regulators in cellular metabolism and are recognized to be nodes in multiple signaling pathways, most notably those involving PI3K/AKT and mTOR. FoxO proteins primarily function as transcription factors, but recent study suggests that cytosolic FoxO1 participates in the r...

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Vydáno v:PLoS One
Hlavní autoři: Zhu, Wan Long, Tong, Honglian, Teh, Jing Tsong, Wang, Mei
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278707/
https://ncbi.nlm.nih.gov/pubmed/25546383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115087
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