The Regulation and Function of the Forkhead Transcription Factor, Forkhead Box O1, Is Dependent on the Progesterone Receptor in Endometrial Carcinoma

In many type I endometrial cancers, the PTEN gene is inactivated, which ultimately leads to constitutively active Akt and the inhibition of Forkhead box O1 (FOXO1), a member of the FOXO subfamily of Forkhead/winged helix family of transcription factors. The expression, regulation, and function of FO...

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Autors principals: Ward, Erin C., Hoekstra, Anna V., Blok, Leen J., Hanifi-Moghaddam, P., Lurain, John R., Singh, Diljeet K., Buttin, Barbara M., Schink, Julian C., Kim, J. Julie
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276720/
https://ncbi.nlm.nih.gov/pubmed/18096667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-0756
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