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Mitochondria distinguish granule-stored from de novo synthesized TNF secretion in human mast cells
BACKGROUND: Mast cells are immune cells derived from hematopoietic precursors that mature in the tissue microenvironment. Mast cells are critical for allergic, immune and inflammatory processes, many of which involve TNF. Mast cells uniquely store TNF in their secretory granules. Upon stimulation, m...
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| Publicado no: | Int Arch Allergy Immunol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4278585/ https://ncbi.nlm.nih.gov/pubmed/22555146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000335178 |
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