IL-9 Induces VEGF Secretion from Human Mast Cells and IL-9/IL-9 Receptor Genes Are Overexpressed in Atopic Dermatitis

Interleukin 9 (IL-9) has been implicated in mast cell-related inflammatory diseases, such as asthma, where vascular endothelial growth factor (VEGF) is involved. Here we report that IL-9 (10–20 ng/ml) induces gene expression and secretion of VEGF from human LAD2. IL-9 does not induce mast cell degra...

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Autors principals: Sismanopoulos, Nikolaos, Delivanis, Danae A., Alysandratos, Konstantinos D., Angelidou, Asimenia, Vasiadi, Magdalini, Therianou, Anastasia, Theoharides, Theoharis C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297631/
https://ncbi.nlm.nih.gov/pubmed/22413008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033271
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