IL-33 augments substance P–induced VEGF secretion from human mast cells and is increased in psoriatic skin

The peptide substance P (SP) has been implicated in inflammatory conditions, such as psoriasis, where mast cells and VEGF are increased. A relationship between SP and VEGF has not been well studied, nor has any interaction with the proinflammatory cytokines, especially IL-33. Here we report that SP...

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Détails bibliographiques
Auteurs principaux: Theoharides, Theoharis C., Zhang, Bodi, Kempuraj, Duraisamy, Tagen, Michael, Vasiadi, Magdalini, Angelidou, Asimenia, Alysandratos, Konstantinos-Dionysios, Kalogeromitros, Dimitris, Asadi, Shahrzad, Stavrianeas, Nikolaos, Peterson, Erika, Leeman, Susan, Conti, Pio
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2010
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840132/
https://ncbi.nlm.nih.gov/pubmed/20160089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000803107
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