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Assessing adaptation of the cancer kinome in response to targeted therapies
Cancer cells are dependent on protein kinase signaling networks to drive proliferation and to promote survival, and accordingly kinases continue to represent a major target class for development of anti-cancer therapeutics. Kinase inhibitors nevertheless have yielded only limited success with many d...
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| Published in: | Biochem Soc Trans |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4278192/ https://ncbi.nlm.nih.gov/pubmed/25109955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20130274 |
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