Complex excitation dynamics underlie polymorphic ventricular tachycardia in a transgenic rabbit model of long QT syndrome type 1

BACKGROUND: Long QT syndrome type 1 (LQT1) is a congenital disease arising from a loss of function in the slowly activating delayed potassium current I(Ks), which causes early afterdepolarizations (EADs) and polymorphic ventricular tachycardia (pVT). OBJECTIVE: The purpose of this study was to inves...

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Detalhes bibliográficos
Publicado no:Heart Rhythm
Main Authors: Kim, Tae Yun, Kunitomo, Yukiko, Pfeiffer, Zachary, Patel, Divyang, Hwang, Jungmin, Harrison, Kathryn, Patel, Brijesh, Jeng, Paul, Ziv, Ohad, Lu, Yichun, Peng, Xuwen, Qu, Zhilin, Koren, Gideon, Choi, Bum-Rak
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277941/
https://ncbi.nlm.nih.gov/pubmed/25285647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2014.10.003
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