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The Scaffold Protein Muscle A-Kinase Anchoring Protein β Orchestrates Cardiac Myocyte Hypertrophic Signaling Required for the Development of Heart Failure

BACKGROUND: Cardiac myocyte hypertrophy is regulated by an extensive intracellular signal transduction network. In vitro evidence suggests that the scaffold protein muscle A-kinase anchoring protein β (mAKAPβ) serves as a nodal organizer of hypertrophic signaling. However, the relevance of mAKAPβ si...

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Detalhes bibliográficos
Publicado no:Circ Heart Fail
Main Authors: Kritzer, Michael D., Li, Jinliang, Passariello, Catherine L., Gayanilo, Marjorie, Thakur, Hrishikesh, Dayan, Joseph, Dodge-Kafka, Kimberly, Kapiloff, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277867/
https://ncbi.nlm.nih.gov/pubmed/24812305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.114.001266
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