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Immune aging and autoimmunity
Age is an important risk for autoimmunity, and many autoimmune diseases preferentially occur in the second half of adulthood when immune competence has declined and thymic T cell generation has ceased. Many tolerance checkpoints have to fail for an autoimmune disease to develop, and several of those...
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| Veröffentlicht in: | Cell Mol Life Sci |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
SP Birkhäuser Verlag Basel
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4277694/ https://ncbi.nlm.nih.gov/pubmed/22466672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-012-0970-0 |
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