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Mechanism of action of tranexamic acid in bleeding trauma patients: an exploratory analysis of data from the CRASH-2 trial

INTRODUCTION: To investigate the mechanism of action of tranexamic acid (TXA) in bleeding trauma patients, we examined the timing of its effect on mortality. We hypothesised that if TXA reduces mortality by decreasing blood loss, its effect should be greatest on the day of the injury when bleeding i...

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Detalhes bibliográficos
Publicado no:Crit Care
Main Authors: Roberts, Ian, Prieto-Merino, David, Manno, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277654/
https://ncbi.nlm.nih.gov/pubmed/25498484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-014-0685-8
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