Immunosuppression after Sepsis: Systemic Inflammation and Sepsis Induce a Loss of Naïve T-Cells but No Enduring Cell-Autonomous Defects in T-Cell Function

Sepsis describes the life-threatening systemic inflammatory response (SIRS) of an organism to an infection and is the leading cause of mortality on intensive care units (ICU) worldwide. An acute episode of sepsis is characterized by the extensive release of cytokines and other mediators resulting in...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Markwart, Robby, Condotta, Stephanie A., Requardt, Robert P., Borken, Farina, Schubert, Katja, Weigel, Cynthia, Bauer, Michael, Griffith, Thomas S., Förster, Martin, Brunkhorst, Frank M., Badovinac, Vladimir P., Rubio, Ignacio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277344/
https://ncbi.nlm.nih.gov/pubmed/25541945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115094
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