Nuclear pore rearrangements and nuclear trafficking in cardiomyocytes from rat and human failing hearts

AIMS: During cardiac hypertrophy, cardiomyocytes (CMs) increase in the size and expression of cytoskeletal proteins while reactivating a foetal gene programme. The process is proposed to be dependent on increased nuclear export and, since nuclear pore trafficking has limited capacity, a linked decre...

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Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Chahine, Mirna N., Mioulane, Maxime, Sikkel, Markus B., O'Gara, Peter, Dos Remedios, Cristobal G., Pierce, Grant N., Lyon, Alexander R., Földes, Gábor, Harding, Sian E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277256/
https://ncbi.nlm.nih.gov/pubmed/25341891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvu218
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