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Mechanisms of Hepatocyte Growth Factor Activation in Cancer Tissues

Hepatocyte growth factor/scatter factor (HGF/SF) plays critical roles in cancer progression through its specific receptor, MET. HGF/SF is usually synthesized and secreted as an inactive proform (pro-HGF/SF) by stromal cells, such as fibroblasts. Several serine proteases are reported to convert pro-H...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Kawaguchi, Makiko, Kataoka, Hiroaki
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276949/
https://ncbi.nlm.nih.gov/pubmed/25268161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers6041890
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