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Mechanisms of Hepatocyte Growth Factor Activation in Cancer Tissues
Hepatocyte growth factor/scatter factor (HGF/SF) plays critical roles in cancer progression through its specific receptor, MET. HGF/SF is usually synthesized and secreted as an inactive proform (pro-HGF/SF) by stromal cells, such as fibroblasts. Several serine proteases are reported to convert pro-H...
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| Udgivet i: | Cancers (Basel) |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4276949/ https://ncbi.nlm.nih.gov/pubmed/25268161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers6041890 |
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