The Hepatitis C Virus Core Protein Inhibits Adipose Triglyceride Lipase (ATGL)-mediated Lipid Mobilization and Enhances the ATGL Interaction with Comparative Gene Identification 58 (CGI-58) and Lipid Droplets

Liver steatosis is a common health problem associated with hepatitis C virus (HCV) and an important risk factor for the development of liver fibrosis and cancer. Steatosis is caused by triglycerides (TG) accumulating in lipid droplets (LDs), cellular organelles composed of neutral lipids surrounded...

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Опубликовано в: :J Biol Chem
Главные авторы: Camus, Gregory, Schweiger, Martina, Herker, Eva, Harris, Charles, Kondratowicz, Andrew S., Tsou, Chia-Lin, Farese, Robert V., Herath, Kithsiri, Previs, Stephen F., Roddy, Thomas P., Pinto, Shirly, Zechner, Rudolf, Ott, Melanie
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2014
Предметы:
Lipids
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276846/
https://ncbi.nlm.nih.gov/pubmed/25381252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.587816
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