The Hepatitis C Virus Core Protein Inhibits Adipose Triglyceride Lipase (ATGL)-mediated Lipid Mobilization and Enhances the ATGL Interaction with Comparative Gene Identification 58 (CGI-58) and Lipid Droplets

Liver steatosis is a common health problem associated with hepatitis C virus (HCV) and an important risk factor for the development of liver fibrosis and cancer. Steatosis is caused by triglycerides (TG) accumulating in lipid droplets (LDs), cellular organelles composed of neutral lipids surrounded...

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Udgivet i:J Biol Chem
Main Authors: Camus, Gregory, Schweiger, Martina, Herker, Eva, Harris, Charles, Kondratowicz, Andrew S., Tsou, Chia-Lin, Farese, Robert V., Herath, Kithsiri, Previs, Stephen F., Roddy, Thomas P., Pinto, Shirly, Zechner, Rudolf, Ott, Melanie
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Lipids
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276846/
https://ncbi.nlm.nih.gov/pubmed/25381252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.587816
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