Iron promotes protein insolubility and aging in C. elegans

Many late-onset proteotoxic diseases are accompanied by a disruption in homeostasis of metals (metallostasis) including iron, copper and zinc. Although aging is the most prominent risk factor for these disorders, the impact of aging on metallostasis and its role in proteotoxic disease remain poorly...

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Podrobná bibliografie
Vydáno v:Aging (Albany NY)
Hlavní autoři: Klang, Ida M., Schilling, Birgit, Sorensen, Dylan J., Sahu, Alexandria K., Kapahi, Pankaj, Andersen, Julie K., Swoboda, Peter, Killilea, David W., Gibson, Bradford W., Lithgow, Gordon J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2014
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276790/
https://ncbi.nlm.nih.gov/pubmed/25554795
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