Iron promotes protein insolubility and aging in C. elegans

Many late-onset proteotoxic diseases are accompanied by a disruption in homeostasis of metals (metallostasis) including iron, copper and zinc. Although aging is the most prominent risk factor for these disorders, the impact of aging on metallostasis and its role in proteotoxic disease remain poorly...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Klang, Ida M., Schilling, Birgit, Sorensen, Dylan J., Sahu, Alexandria K., Kapahi, Pankaj, Andersen, Julie K., Swoboda, Peter, Killilea, David W., Gibson, Bradford W., Lithgow, Gordon J.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276790/
https://ncbi.nlm.nih.gov/pubmed/25554795
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