Mesenchymal chemotaxis requires selective inactivation of Myosin II at the leading edge via a non-canonical PLCγ/PKCα pathway

Chemotaxis, migration towards soluble chemical cues, is critical for processes such as wound healing and immune surveillance, and is exhibited by various cell types from rapidly-migrating leukocytes to slow-moving mesenchymal cells. To interrogate the mechanisms involved in mesenchymal chemotaxis, w...

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Publicado en:Dev Cell
Main Authors: Asokan, Sreeja B., Johnson, Heath E., Rahman, Anisur, King, Samantha J., Rotty, Jeremy D., Lebedeva, Irina P., Haugh, Jason M., Bear, James E.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276478/
https://ncbi.nlm.nih.gov/pubmed/25482883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.10.024
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