A Reaction-Diffusion Model Explains Amplification of the PLC/PKC Pathway in Fibroblast Chemotaxis

During the proliferative phase of cutaneous wound healing, dermal fibroblasts are recruited into the clotted wound by a concentration gradient of platelet-derived growth factor (PDGF), together with other spatial cues. Despite the importance of this chemotactic process, the mechanisms controlling th...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Mohan, Krithika, Nosbisch, Jamie L., Elston, Timothy C., Bear, James E., Haugh, Jason M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Systems Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510763/
https://ncbi.nlm.nih.gov/pubmed/28700916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.05.035
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