Brain Cell Death is reduced with Cooling by 3.5°C to 5°C but increased with Cooling by 8.5°C in a Piglet Asphyxia Model

BACKGROUND AND PURPOSE: In infants with moderate to severe neonatal encephalopathy, whole body cooling to 33-34°C for 72 hours is standard care with a number needed to treat to prevent one adverse outcome of 6-7. The precise brain temperature providing optimal neuroprotection is unknown. METHODS: Af...

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Publicado en:Stroke
Autores principales: Alonso-Alconada, Daniel, Broad, Kevin D, Bainbridge, Alan, Chandrasekaran, Manigandan, Faulkner, Stuart D, Kerenyi, Áron, Hassell, Jane, Eridan Rocha-Ferreira, E, Hristova, Mariya, Fleiss, Bobbi, Bennett, Kate, Kelen, Dorottya, Cady, Ernest, Gressens, Pierre, Golay, Xavier, Robertson, Nicola J
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276417/
https://ncbi.nlm.nih.gov/pubmed/25424475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.114.007330
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