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Molecular Modeling Studies of Thiophenyl C-Aryl Glucoside SGLT2 Inhibitors as Potential Antidiabetic Agents

A QSAR study on thiophenyl derivatives as SGLT2 inhibitors as potential antidiabetic agents was performed with thirty-three compounds. Comparison of the obtained results indicated the superiority of the genetic algorithm over the simulated annealing and stepwise forward-backward variable method for...

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Bibliografiske detaljer
Udgivet i:Int J Med Chem
Main Authors: Sharma, Mukesh C., Sharma, Smita
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276301/
https://ncbi.nlm.nih.gov/pubmed/25574393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/739646
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