Prostaglandin E(1) Effects on Adenosine 3′:5′-Cyclic Monophosphate Concentration and Phosphodiesterase Activity in Fibroblasts
Incubation of L-929 and L-2071 fibroblasts with prostaglandin E(1) (PGE(1)) caused a rapid increase in the cyclic AMP content of these cells. A maximal effect was produced with 0.2 μg PGE(1) per ml. At a concentration of 4 μg/ml, PGE(2) was almost equally effective, but PGF(2α) and PGA(2) were much...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1972
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427589/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4333044/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.1.269 |
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