The Impact of Early Intra-Articular Administration of Interleukin-1 Receptor Antagonist on Lubricin Metabolism and Cartilage Degeneration in an Anterior Cruciate Ligament Transection Model

OBJECTIVE: Study the impact of intra-articular interleukin-1 receptor antagonist (IL-1 ra) treatment on lubricin biosynthesis following anterior cruciate ligament transection (ACLT) in the rat and evaluate the effect of combined IL-1 ra and recombinant human lubricin (rhPRG4) treatments on chondrocy...

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Pubblicato in:Osteoarthritis Cartilage
Autori principali: Elsaid, KA, Zhang, L, Shaman, Z, Patel, C, Schmidt, TA, Jay, GD
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275352/
https://ncbi.nlm.nih.gov/pubmed/25219670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2014.09.006
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