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The Impact of Anterior Cruciate Ligament Injury on Lubricin Metabolism and the Effect of Inhibiting TNF-α on Chondroprotection in an Animal Model

OBJECTIVE: To examine the effects of ACL transection (ACLT) in a rat model on lubricin metabolism and its relationship to markers of inflammation and cartilage damage, and to determine if blocking the metabolic effects of tumor necrosis factor-alpha (TNF-α), by etanercept increases chondroprotection...

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Main Authors: Elsaid, KA, Machan, JT, Waller, K, Fleming, BC, Jay, GD
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800051/
https://ncbi.nlm.nih.gov/pubmed/19790069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.24800
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