Methylation of Histone H3 by Set2 in Saccharomyces cerevisiae Is Linked to Transcriptional Elongation by RNA Polymerase II

Set2 methylates Lys36 of histone H3. We show here that yeast Set2 copurifies with RNA polymerase II (RNAPII). Chromatin immunoprecipitation analyses demonstrated that Set2 and histone H3 Lys36 methylation are associated with the coding regions of several genes that were tested and correlate with act...

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Hauptverfasser: Krogan, Nevan J., Kim, Minkyu, Tong, Amy, Golshani, Ashkan, Cagney, Gerard, Canadien, Veronica, Richards, Dawn P., K. Beattie, Bryan, Emili, Andrew, Boone, Charles, Shilatifard, Ali, Buratowski, Stephen, Greenblatt, Jack
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Transcriptional Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC427527/
https://ncbi.nlm.nih.gov/pubmed/12773564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.12.4207-4218.2003
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