Methylation of Histone H3 by Set2 in Saccharomyces cerevisiae Is Linked to Transcriptional Elongation by RNA Polymerase II

Set2 methylates Lys36 of histone H3. We show here that yeast Set2 copurifies with RNA polymerase II (RNAPII). Chromatin immunoprecipitation analyses demonstrated that Set2 and histone H3 Lys36 methylation are associated with the coding regions of several genes that were tested and correlate with act...

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Detalhes bibliográficos
Main Authors: Krogan, Nevan J., Kim, Minkyu, Tong, Amy, Golshani, Ashkan, Cagney, Gerard, Canadien, Veronica, Richards, Dawn P., K. Beattie, Bryan, Emili, Andrew, Boone, Charles, Shilatifard, Ali, Buratowski, Stephen, Greenblatt, Jack
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC427527/
https://ncbi.nlm.nih.gov/pubmed/12773564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.12.4207-4218.2003
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