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T Cell Factor-1 Controls the Lifetime of CD4+ CD8+ Thymocytes In Vivo and Distal T Cell Receptor α-Chain Rearrangement Required for NKT Cell Development

Natural killer T (NKT) cells are a component of innate and adaptive immune systems implicated in immune, autoimmune responses and in the control of obesity and cancer. NKT cells develop from common CD4+ CD8+ double positive (DP) thymocyte precursors after the rearrangement and expression of T cell r...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Sharma, Archna, Berga-Bolaños, Rosa, Sen, Jyoti Misra
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275257/
https://ncbi.nlm.nih.gov/pubmed/25536344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115803
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