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Implications of Targeted Genomic Disruption of β-Catenin in BxPC-3 Pancreatic Adenocarcinoma Cells

Pancreatic adenocarcinoma (PA) is among the most aggressive human tumors with an overall 5-year survival rate of <5% and available treatments are only minimal effective. WNT/β-catenin signaling has been identified as one of 12 core signaling pathways that are commonly mutated in PA. To obtain mor...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Olsen, Petter Angell, Solberg, Nina Therese, Lund, Kaja, Vehus, Tore, Gelazauskaite, Monika, Wilson, Steven Ray, Krauss, Stefan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275244/
https://ncbi.nlm.nih.gov/pubmed/25536063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115496
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