Simple Radiometric Method for Accurately Quantitating Epitope Densities of Hapten–Protein Conjugates with Sulfhydryl Linkages

[Image: see text] Control of small molecule hapten epitope densities on antigenic carrier proteins is essential for development and testing of optimal conditions for vaccines. Yet, accurate determination of epitope density can be extremely difficult to accomplish, especially with the use of small ha...

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Библиографические подробности
Опубликовано в: :Bioconjug Chem
Главные авторы: Peterson, Eric C., Hambuchen, Michael D., Tawney, Rachel L., Gunnell, Melinda G., Cowell, James L., Lay, Jackson O., Blough, Bruce E., Carroll, F. Ivy, Owens, S. Michael
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2014
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275166/
https://ncbi.nlm.nih.gov/pubmed/25426820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc500456z
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